The collection consists of correspondence between Daniel Coit Gilman, Basil Gildersleeve, Nicholas Murray Butler and others regarding obtaining a copy of the Didache manuscript.

Johns Hopkins (1795-1873) was a highly successful Baltimore merchant and philanthropist. He left much of his wealth to found a university and hospital in Baltimore. This collection contains manuscripts, photographs and printed material by or about Johns Hopkins and his ancestors, 1743-2005.

This collection consists of Hugh Hawkins including a two volume typescript of Hawkins' published work Pioneer : a history of the Johns Hopkins University, 1874-1899 and other material, including correspondence and photographs.

The News-Letter, one of the oldest and most successful student organizations at Johns Hopkins, began in the Spring of 1897. This collection consists of News-Letter volumes in various formats from 1897 to present.

The University history scrapbooks collection contains 34 volumes of newspaper clippings and articles featuring Johns Hopkins University history and notable accomplishments by its faculty and students from approximately the 1840s to the 1980s.

The Vertical Reference File is an "artificial" collection consisting of newspaper clippings, magazine articles, curriculum vitaes, and other informational materials concerning Hopkins-related topics, such as individuals, buildings, athletic events, and lecture series. Files on individuals often contain obituaries or other biographical materials.