This subseries contains files associated with project and grant requests that Mikulski's office received. Project files document assistance from Mikulski's office to an organization or community in their interactions with one or more federal agencies on an issue.

This subseries contains photographs and photographic negatives from across Mikulski's life, with the bulk of materials produced during her Senate years. Materials include official portraits, event photos, and photos with staff.

This subseries contains correspondence, scheduling materials and meeting notes for Mikulski and her staff, travel records, political planning materials, and administrative files associated with Mikulski's office operations in Washington, DC and state offices. Examples of material that may be found in this subseries include staff manuals, "NAV" folders prepared to brief Mikulski for events and meetings, staff memos, form letters, and constituent correspondence.